Our lab’s mission is to understand immune defense quantitatively using theory and computation.
We are a Quantitative Immunology research group in the Division of Infection and Immunity at UCL. Our research is embedded within the collaborative environment of the Innate2Adaptive lab group and we have strong links with experimental and theory groups at UCL and beyond.
Our approach to quantitative immunology is rooted in the tradition of biological physics and we are part of UCL’s Institute for the Physics of Living Systems.
News
- On March 9th 2023 we are organizing a London Quantitative Immunology Day. Come join us!
- Sept 30 2022: The workshop “Statistical physics and adaptive immunity” co-organized by Andreas is now open for registration. The workshop will be held at the Aspen Center for Physics August 6 - 27, 2023.
- July 25 2022: First paper from lab out on bioRxiv! Our first foray into deciphering TCR specificity quantitatively.
- Apr 7 2022: The lab opens its doors at UCL!
- Mar 15 2022: Andreas gave an invited talk at the APS march meeting in the Sensing chemical spaces session.
- Mar 5 2020: Andreas gave an invited (virtual) talk at the APS march meeting in the Population dynamics in time-varying environments session.
- December 11-13 2019: We have organized a conference at PCTS on Sensing chemical spaces. Video recordings of the lectures are available here.
Selected Publications
A Mayer, C Callan Measures of epitope binding degeneracy from T cell receptor repertoires, PNAS, 2023.
H Chen, A Mayer, V Balasubramanian A scaling law in CRISPR repertoire sizes arises from avoidance of autoimmunity, Current Biology, 2022.
MG Gaimann, M Nguyen, J Desponds, A Mayer, Early life imprints the hierarchy of T cell clone sizes, eLife, 2020.
A Mayer, Y Zhang, AS Perelson, NS Wingreen, Regulation of T cell expansion by antigen presentation dynamics, PNAS, 2019.
A Mayer, O Rivoire, T Mora, and AM Walczak, Diversity of immune strategies explained by adaptation to pathogen statistics, PNAS, 2016.
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